A three-part documentary series that tells the story of how women overcame gender discrimination and segregation on America's most beloved road. This series documents the extraordinary lives and achievements of women who overcame gender discrimination and segregation to build fulfilling lives and legacies on America's most iconic highway. From entrepreneurs and waitresses, anthropologists and politicians, to artists and military sergeants, these women transformed their communities and the American West through their hard work, perseverance and ingenuity. In the 1950s, the creation of interstate highways began the death toll for Route 66. Environmental disaster and unemployment caused by changing models of transportation also dealt blows to many small towns. Women were at the forefront of fighting to keep their main streets alive. Women have been leading revitalization projects that keep the lights on in their communities, boost the local economy and preserve American History for generations to come.